For a short introduction to our Open-Hardware Support service, please watch this video and get in touch, should you crave more information.
Please note: NeuroGig also offers complete component kits for clients who prefer not to purchase components from multiple suppliers listed on the Bill-of Materials.
Scroll down to see our current open-source hardware projects.
Riding the wave of the recent DIY and open-source hardware trend, NeuroGig offers a service where it supports increased uptake of a select few, but commonly-used open-source Neuroscience instruments.
We are currently compiling a list of typical instruments we are able to build. Part of this process includes receiving nominations from the Neuroscience community.
Therefore, if your laboratory needs an open-source instrument, please get in touch. We may be able to assist.
How does this service work?
We provide you with a parts list and quotes from various suppliers according to the open-source design. You place the order and have it delivered to our workshop on the farm. NeuroGig handles assembly and testing at a nominal fee.
We also offer installation, training and technical support services as further options.
We have listed our trusted suppliers in the Bill of Materials Calculator document.
Alternatively, buy a hassle-free Faraday Cage Kit from us and we will even label the parts for you to simplify the build even more.
Get in touch with our helpful team and we will recommend the best Faraday Cage solution for your project and send you a ready to build Faraday Cage Kit.
Our technicians would be happy to help in assembly of each cage panel and provide support with installation of the cage.
The ability to precisely deliver picolitre volumes has always been a vital part of Biological research, until now this has required a significant investment of up to £4,500 into an established brand.
The Openspritzer (developed, described and published by Forman et al., 2017) serves as an alternative open-source micro-ejection/puffer system with similar performance and reliability that you would expect from leading brands, but at a fraction of the cost.
As with the more familiar models on the market, the Openspritzer is a self-contained system that has been designed to be intuitive, with simple functionality. Featuring a built-in ejection control system which is easily adjusted using a rotary switch you have complete control of the ejection duration; you also have the option of controlling the duration via a remotely generated TTL pulse. Ejection pressure is adjusted via the built-in regulator along with an accurate monitoring gauge. The Openspritzer is also supplied with a foot switch for added ease of operation.
NeuroGig's Open-Hardware Support now offers the Openspritzer, to order as a complete unit (component kit, plus assembly and testing). We can further leave the purchasing of the components to you, and have it delivered to our workshop to handle assembly, testing and installation/support.
Valve Type -
114mA Fast switching Solenoid
Power supply -
24V DC supply for solenoid valve
1mA/5V Internally generated pulses from Arduino Nano microcontroller
Externally delivered TTL pulses via BNC connector
Foot switch -
Air regulator -
TTL trains -
Yes, at 10Hz TTL train with altered line pressure generated action potentials, but not at 2 or 5Hz
*single puff of glutamate insufficient to activate action potential
Shortest command pulse -
*to reliably generate a detectable puff
*in comparison with 4ms for Picospritzer
Puff pressure -
Line pressure -
Millisecond precision with highly conserved puff volumes
Tested for use -
*Evoking and suppression of action potentials
*In vitro whole cell patch clamp recordings
*Microinjections of infectious agents
*Viral delivery of opsins for optogenetics
*Single molecules to whole bacteria
*Inoculate brain tissue slices with BCG-GFP
*In rodent and human brain slices
1) A lateral offset between normalised peak intensities, where e.g. the Picospritzer can deliver smaller doses for a given puff duration
*this difference could also be due to small differences in pressure. Whilst both instruments were set to 1.4bar, there could be internal pneumatic differences in the complete systems
2) Variability of the dosage on repeated puffs
The Openspritzer sometimes delivers slightly higher doses at the same settings as the Picospritzer, but this could also be an artefact
*Openspritzer puffs were set at one second delays in between pulses whilst Picospritzer pulses were set and triggered manually
3) Absence of intermediate pressure to prevent back filling in the off state
*this function could easily be added with another regulator at port 3 of the solenoid valve
4) Vacuum holding capacity to hold cells in place
*this could easily be accomplished with another Openspritzer in tandem
5) Complete access to the source code for the control of the Openspritzer
*this provides users with an increased range of parameters for controlling timing and puff duration
The NeuroGig Open-Hardware Support service now has the complete kit for the Openspritzer to order. The kit includes all parts and materials in the correct amounts/sizes, for an efficient and cost-effective instrument assembly.
If you would like to purchase the items directly from multiple suppliers, please let us know and we will send you the BOM.
Please remember that we are always happy to assist with assembly, testing and installation.
For more information on the Open-Hardware Support we offer, please see our short introduction video.
Please get in touch for an itemised quote for the Openspritzer, or book a meeting should you have any further questions.
Definitely. NeuroGig offers assembly, testing and a workmanship warranty. So, if you have already purchased the parts or the NeuroGig complete kit, but you struggle to find the time for the build or just don't have the patience...we are ready to help.