Easter Sale – Up to 33% Off the Tools That Keep Your Rig Running Cleanly
A patch-clamp and imaging rig represents an investment of €80,000 or more in equipment — yet the peripheral tools that determine data quality and experimental uptime are often an afterthought. Temperature drift in the perfusion line changes the electrophysiological properties of your preparation. Air bubbles disrupt recordings. Spills cause noise, downtime, and in the worst cases, hardware damage. And proprietary microinjection systems cost several thousand pounds for performance that open-source alternatives now match, as documented in peer-reviewed benchmarking. NeuroGig builds the instruments that serious neurophysiology labs rely on to keep their rigs running cleanly, their data reproducible, and their budgets intact — at open-source prices, with full access to the hardware and software underneath. That’s what makes now a good time to upgrade.
Time-Limited Offer
Why Labs Are Upgrading Their Rigs Right Now
On the cost of commercial microinjection systems:
Huge investment with proprietary systems
Commercial pressure-ejection systems capable of millisecond-precision puff delivery have historically required investment in the range of several thousand pounds — typically in the range of several thousands of pounds ScienceDirect — placing them out of reach for many labs, particularly those in lower-funded institutions or developing countries.
Open-source instrument produces excellent results compared to proprietary systems
The OpenSpritzer matches the performance of leading commercial systems: peer-reviewed two-photon fluorescence benchmarking demonstrated that open-source pressure ejection provides the same level of control over delivered reagent dose as the commercial system.
Technically superior open-source systems
A key technical advantage over older commercial systems: the OpenSpritzer achieves a shortest command pulse of 2ms — compared to 4ms for the PicoSpritzer — giving researchers tighter temporal control over drug and neurotransmitter delivery.
Open-source is more versatile
Versatility across applications is a documented strength: OpenSpritzer has been validated for neurotransmitter puffing, viral vector delivery for optogenetics, and bacterial microinjection into living tissue — suitable for delivering infectious agents including viral delivery of opsins for optogenetics
On perfusion temperature and stability:
Impact of perfusion temperature instability
Temperature drift during perfusion is not a cosmetic issue — it changes fundamental neuronal properties. Research has directly demonstrated that striatal medium spiny neurons exhibit increased membrane resistance, longer membrane time constants, lower firing rates, and increased rheobase current at room temperature compared to physiological temperature, meaning uncontrolled temperature = unreliable data.
Complexity and cost of proprietary systems
Maintaining perfusate at a specific temperature throughout applications requires heaters with integrated feedback systems, which has historically increased complexity and cost — making such systems prohibitively expensive in research environments with lower funding rates, particularly in the current funding environment and in developing countries.
Accurate and versatile in-line heater as an option
Inline heating is now the expected standard: modern temperature control systems continuously monitor temperature in the recording chamber and apply heating to the ACSF in or just before reaching the recording chamber — such in-line heating solutions have become the standard in high-quality electrophysiological research.
Low-noise heater design
Temperature also has a direct effect on electrical noise: electrical disturbances may be induced by control operations of tempering elements (e.g., switching them on and off) if these elements are placed in proximity to recording electrodes — making tested, low-noise heating design a critical specification, not an afterthought.
On spills and rig damage:
Data loss because of spills
Spills are a known and recurring source of data loss: rig flooding Python Forum is cited alongside bubble formation and unexplained noise as the most common causes of experiment failure in patch-clamp labs — and a rig costs an easy €80k to replace!
Causes messy and unpredictable noise
Salt solution spills create more than just a mess — spillages and dried salt around the bath may lead to noise from an electrochemical junction, appearing as unstable, fluctuating noise on a timescale of milliseconds to seconds — caused by salt solution that creates a battery between dissimilar metals, or that bridges different ground connections
On perfusion flow and bubble management:
Prevent experimental disruption
Air bubble formation in the perfusion line is one of the most universally reported sources of experiment disruption in patch-clamp labs. Accurate control of perfusion speed and temperature of the perfusate reduce chances of bubble formation. The open-source nature of our designs means total control in the hands of the end-user
Flow rate - find the sweet spot
Perfusion flow rate is a critical variable that is easily overlooked: a perfusion speed over 2 mL per minute might lead to movements of the recording pipette and lifting of cells from the coverslip, whilst some brain slice experiments require faster flow rates to improve long-term tissue viability and function— programmable, stable, low-pulsation flow control is therefore directly relevant to data quality.
Two Ways to Equip Your Lab
Option 1: Single Item Savings
Option 2: NeuroGig Instrument Bundles (Big Discounts)
Perfusion Confidence Kit
New Rig Starter Bundle
OpenBase + OpenStage + OpenSpritzer + Rig Guardian – 23% off with voucher. Additional 12% for prepayment for a 33% total discount.
Rig Protection Pack
OpenFlowCtrl Peristaltic Pump with integrated Rig Guardian + 4-sensor expansion – free extra sensors and 15% total discount
Know a Colleague Who May Benefit from this Offer?
Receive a Free Rig Guardian Spill Detector for your lab
Share your unique voucher code with collaborators or network members. When they make a qualifying purchase and reference you, we’ll ship a Rig Guardian spill detector directly to your lab at no cost.
Steps:
- Request voucher below. The voucher will be linked to your name.
- Forward the voucher to your contact.
- When your contact orders with your voucher, your Rig Guardian Spill Detector will be shipped to you, free of charge.
Rig Guardian Spill Detector Short Demo
Designed and Built for Neurophysiology Labs
- 2-Year Warranty on all instruments
- 30-Day No-Risk Return Policy
- Priority Support: Responses within 24-48 hours
- Fully Open-Source: Access designs for transparency and customization
Frequently Asked Questions - Europe End-of-Winter Offer
How do I request a voucher?
What is the prepayment process?
Shipping details and cost?
Shipments to be done via DHL Express International from our workshop in South Africa to Europe. Shipping cost will be quoted separately, depending on box volume and weight.
Complimentary Rig Guardian Spill Detectors will be shipped free of charge.
Estimated delivery time will be quoted separately, but is typically between 3 and 8 weeks from date of order received.
